TC21 causes transformation by Raf-independent signaling pathways.

Although the Ras-related protein TC21/R-Ras2 has only 55% amino acid identity with Ras proteins, mutated forms of TC21 exhibit the same potent transforming activity as constitutively activated forms of Ras. Therefore, like Ras, TC21 may activate signaling pathways that control normal cell growth and...

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Hlavní autoři: Graham, S M, Vojtek, A B, Huff, S Y, Cox, A D, Clark, G J, Cooper, J A, Der, C J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC231616/
https://ncbi.nlm.nih.gov/pubmed/8887643
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