TC21 causes transformation by Raf-independent signaling pathways.

Lignende værker

• Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.
  af: Khosravi-Far, R, et al.
  Udgivet: (1996)
• Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells.
  af: Rosário, M, et al.
  Udgivet: (1999)
• Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.
  af: Graham, S M, et al.
  Udgivet: (1994)
• A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function.
  af: Fabian, J R, et al.
  Udgivet: (1994)
• Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells.
  af: Oldham, S M, et al.
  Udgivet: (1996)