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Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway
The chemotherapeutic agent cisplatin is widely used in treatment of solid tumors. In breast cancer cells, cisplatin produces early and marked changes in cell morphology and the actin cytoskeleton. These changes manifest as loss of lamellipodia/filopodia and appearance of membrane ruffles. Furthermor...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2315679/ https://ncbi.nlm.nih.gov/pubmed/18426979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705060 |
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