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A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis

It is now appreciated that sphingolipids constitute a rich class of bioactive molecules that include ceramide, sphingosine, and sphingosine 1-phosphate whose formation is controlled by a network of highly regulated enzymes (Hannun & Obeid, 2008). Notably, several stress stimuli induce the produc...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Hannun, Yusuf A, Newcomb, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459812/
https://ncbi.nlm.nih.gov/pubmed/25859016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505161
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