Negative regulation of Raf-1 by phosphorylation of serine 621.

The elevation of cyclic AMP (cAMP) levels in the cell downregulates the activity of the Raf-1 kinase. It has been suggested that this effect is due to the activation of cAMP-dependent protein kinase (PKA), which can directly phosphorylate Raf-1 in vitro. In this study, we confirmed this hypothesis b...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Mischak, H, Seitz, T, Janosch, P, Eulitz, M, Steen, H, Schellerer, M, Philipp, A, Kolch, W
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC231540/
https://ncbi.nlm.nih.gov/pubmed/8816453
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items