The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.

Ítems similars

• YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.
  per: Myers, M G, et al.
  Publicat: (1996)
• Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase.
  per: Mèndez, R, et al.
  Publicat: (1996)
• Insulin-stimulated oocyte maturation requires insulin receptor substrate 1 and interaction with the SH2 domains of phosphatidylinositol 3-kinase.
  per: Chuang, L M, et al.
  Publicat: (1993)
• Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction.
  per: Rose, D W, et al.
  Publicat: (1994)
• Role of IRS-1-GRB-2 complexes in insulin signaling.
  per: Myers, M G, et al.
  Publicat: (1994)