The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.

The Drosophila insulin receptor (DIR) contains a 368-amino-acid COOH-terminal extension that contains several tyrosine phosphorylation sites in YXXM motifs. This extension is absent from the human insulin receptor but resembles a region in insulin receptor substrate (IRS) proteins which binds to the...

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Detalhes bibliográficos
Main Authors: Yenush, L, Fernandez, R, Myers, M G, Grammer, T C, Sun, X J, Blenis, J, Pierce, J H, Schlessinger, J, White, M F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC231240/
https://ncbi.nlm.nih.gov/pubmed/8628319
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