YMXM motifs of IRS-1 define substrate specificity of the insulin receptor kinase.

Of 34 tyrosine residues in insulin receptor substrate 1 (IRS-1), 14 are adjacent to acidic residues, suggesting that they might be phosphorylation sites. Synthetic peptides corresponding to sequences surrounding these tyrosines were used as substrates of the insulin receptor kinase. Surprisingly six...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shoelson, S E, Chatterjee, S, Chaudhuri, M, White, M F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312712/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2027
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!