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Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain.

To assess the function of the cytoplasmic domain of the insulin receptor (IR) beta subunit, we have studied a mutant IR truncated by 365 aa (HIR delta 978), thereby deleting > 90% of the cytoplasmic domain. HIR delta 978 receptors were processed normally to homodimers that were expressed at the c...

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Detalhes bibliográficos
Main Authors: Sasaoka, T, Takata, Y, Kusari, J, Anderson, C M, Langlois, W J, Olefsky, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC46514/
https://ncbi.nlm.nih.gov/pubmed/8506276
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