The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.

The Drosophila insulin receptor (DIR) contains a 368-amino-acid COOH-terminal extension that contains several tyrosine phosphorylation sites in YXXM motifs. This extension is absent from the human insulin receptor but resembles a region in insulin receptor substrate (IRS) proteins which binds to the...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Yenush, L, Fernandez, R, Myers, M G, Grammer, T C, Sun, X J, Blenis, J, Pierce, J H, Schlessinger, J, White, M F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231240/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628319/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.5.2509
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