IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice.

類似資料

• A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells.
  著者:: Shumway, Stuart D, 等
  出版事項: (2004)
• Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.
  著者:: Wulczyn, F G, 等
  出版事項: (1998)
• Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha.
  著者:: Schwarz, E M, 等
  出版事項: (1996)
• Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation.
  著者:: DeLuca, C, 等
  出版事項: (1996)
• Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB pathways
  著者:: Zhou, Zheng, 等
  出版事項: (2019)