The TCL1A oncoprotein interacts directly with the NF-kappaB inhibitor IkappaB.
The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its pleckstrin homology (PH) domain. However, perturbatio...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2009-08-01
|
| Colección: | PLoS ONE |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19668332/pdf/?tool=EBI |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|