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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain.

A number of homeodomain proteins have been shown to regulate cellular development by stimulating the transcription of specific target genes. In contrast to their distinct activities in vivo, however, most homeodomain proteins bind indiscriminately to potential target sites in vitro, suggesting the i...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Peers, B, Sharma, S, Johnson, T, Kamps, M, Montminy, M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.7091
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