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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain.

A number of homeodomain proteins have been shown to regulate cellular development by stimulating the transcription of specific target genes. In contrast to their distinct activities in vivo, however, most homeodomain proteins bind indiscriminately to potential target sites in vitro, suggesting the i...

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Publicado en:Mol Cell Biol
Autores principales: Peers, B, Sharma, S, Johnson, T, Kamps, M, Montminy, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1995
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.7091
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