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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain.

A number of homeodomain proteins have been shown to regulate cellular development by stimulating the transcription of specific target genes. In contrast to their distinct activities in vivo, however, most homeodomain proteins bind indiscriminately to potential target sites in vitro, suggesting the i...

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Pubblicato in:Mol Cell Biol
Autori principali: Peers, B, Sharma, S, Johnson, T, Kamps, M, Montminy, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1995
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.7091
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