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The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain.

A number of homeodomain proteins have been shown to regulate cellular development by stimulating the transcription of specific target genes. In contrast to their distinct activities in vivo, however, most homeodomain proteins bind indiscriminately to potential target sites in vitro, suggesting the i...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Peers, B, Sharma, S, Johnson, T, Kamps, M, Montminy, M
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.7091
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