RAS signalling is abnormal in a c-raf1 MEK1 double mutant.
A mutant rat cell clone that suppresses the transformation defects of RAS effector loop substitutions is heterozygous for mutations in c-raf1 and MEK1. The mutant cells can be transformed by many otherwise defective RAS effector mutants, including RAS genes with the effector regions of distantly rel...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1995
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230758/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.5113 |
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