Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes.

Stimulation of T cells with antibodies directed towards the T cell receptor complex results in the activation of mitogen-associated protein kinase (MAPK). Two pathways have been described in other cell types that can lead to MAPK activation. One of these pathways involves the activation of Ras, lead...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Franklin, R A, Tordai, A, Patel, H, Gardner, A M, Johnson, G L, Gelfand, E W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8182145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117209
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