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RAS signalling is abnormal in a c-raf1 MEK1 double mutant.

A mutant rat cell clone that suppresses the transformation defects of RAS effector loop substitutions is heterozygous for mutations in c-raf1 and MEK1. The mutant cells can be transformed by many otherwise defective RAS effector mutants, including RAS genes with the effector regions of distantly rel...

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Udgivet i:Mol Cell Biol
Principais autores: Bottorff, D, Stang, S, Agellon, S, Stone, J C
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651428/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.5113
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