RAS signalling is abnormal in a c-raf1 MEK1 double mutant.

A mutant rat cell clone that suppresses the transformation defects of RAS effector loop substitutions is heterozygous for mutations in c-raf1 and MEK1. The mutant cells can be transformed by many otherwise defective RAS effector mutants, including RAS genes with the effector regions of distantly rel...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Bottorff, D, Stang, S, Agellon, S, Stone, J C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230758/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.9.5113
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