Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein
We are interested in using recombinant adeno-associated viral vectors in the treatment of hemophilia A. Because of the size constraints of recombinant adeno-associated viral vectors, we delivered the heavy and light chains of the human factor 8 (hFVIII) cDNA independently by using two separate vecto...
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| Опубліковано в:: | Proc Natl Acad Sci U S A |
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| Автори: | , , , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1999
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23069/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535990/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12725 |
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