PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

The serine/threonine kinase PAK4 is a target for the Rho GTPase Cdc42 and has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells. To examine the physiological and developmental functions of PAK4, we have disrupted the PAK4 gene in mice. The absence of PAK4 led to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Qu, Jian, Li, Xiaofan, Novitch, Bennet G., Zheng, Ye, Kohn, Matthew, Xie, Jian-Ming, Kozinn, Spencer, Bronson, Roderick, Beg, Amer A., Minden, Audrey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230313/
https://ncbi.nlm.nih.gov/pubmed/14517283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7122-7133.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados