Targeted Disruption of the Meprin β Gene in Mice Leads to Underrepresentation of Knockout Mice and Changes in Renal Gene Expression Profiles

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded α and/or β subunits. Homooligomers of meprin α are...

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מידע ביבליוגרפי
Main Authors: Norman, Lourdes P., Jiang, Weiping, Han, Xiaoli, Saunders, Thomas L., Bond, Judith S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2003
נושאים:
Mammalian Genetic Models with Minimal or Complex Phenotypes
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC141138/
https://ncbi.nlm.nih.gov/pubmed/12556482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1221-1230.2003
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