Targeted Disruption of the Meprin β Gene in Mice Leads to Underrepresentation of Knockout Mice and Changes in Renal Gene Expression Profiles

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded α and/or β subunits. Homooligomers of meprin α are...

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Detalhes bibliográficos
Main Authors: Norman, Lourdes P., Jiang, Weiping, Han, Xiaoli, Saunders, Thomas L., Bond, Judith S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141138/
https://ncbi.nlm.nih.gov/pubmed/12556482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1221-1230.2003
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