Targeted Disruption of the Meprin β Gene in Mice Leads to Underrepresentation of Knockout Mice and Changes in Renal Gene Expression Profiles

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded α and/or β subunits. Homooligomers of meprin α are...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Norman, Lourdes P., Jiang, Weiping, Han, Xiaoli, Saunders, Thomas L., Bond, Judith S.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Mammalian Genetic Models with Minimal or Complex Phenotypes
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12556482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.4.1221-1230.2003
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