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PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development
The serine/threonine kinase PAK4 is a target for the Rho GTPase Cdc42 and has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells. To examine the physiological and developmental functions of PAK4, we have disrupted the PAK4 gene in mice. The absence of PAK4 led to...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC230313/ https://ncbi.nlm.nih.gov/pubmed/14517283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7122-7133.2003 |
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