PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

The serine/threonine kinase PAK4 is a target for the Rho GTPase Cdc42 and has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells. To examine the physiological and developmental functions of PAK4, we have disrupted the PAK4 gene in mice. The absence of PAK4 led to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Qu, Jian, Li, Xiaofan, Novitch, Bennet G., Zheng, Ye, Kohn, Matthew, Xie, Jian-Ming, Kozinn, Spencer, Bronson, Roderick, Beg, Amer A., Minden, Audrey
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2003
Θέματα:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC230313/
https://ncbi.nlm.nih.gov/pubmed/14517283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.20.7122-7133.2003
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια