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An optimal Mg(2+) concentration for kinetic folding of the Tetrahymena ribozyme

Divalent metal ions, such as Mg(2+), are generally required for tertiary structure formation in RNA. Although the role of Mg(2+) binding in RNA-folding equilibria has been studied extensively, little is known about the role of Mg(2+) in RNA-folding kinetics. In this paper, we explore the effect of M...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rook, Martha S., Treiber, Daniel K., Williamson, James R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535946/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12471
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