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An optimal Mg(2+) concentration for kinetic folding of the Tetrahymena ribozyme

Divalent metal ions, such as Mg(2+), are generally required for tertiary structure formation in RNA. Although the role of Mg(2+) binding in RNA-folding equilibria has been studied extensively, little is known about the role of Mg(2+) in RNA-folding kinetics. In this paper, we explore the effect of M...

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Detalhes bibliográficos
Main Authors: Rook, Martha S., Treiber, Daniel K., Williamson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22953/
https://ncbi.nlm.nih.gov/pubmed/10535946
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