Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

Mutations of von Hippel–Lindau disease (VHL) tumor-suppressor gene product (pVHL) are found in patients with dominant inherited VHL syndrome and in the vast majority of sporadic clear cell renal carcinomas. The function of the pVHL protein has not been clarified. pVHL has been shown to form a comple...

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ग्रंथसूची विवरण

में प्रकाशित:	Proc Natl Acad Sci U S A
मुख्य लेखकों:	Iwai, Kazuhiro, Yamanaka, Koji, Kamura, Takumi, Minato, Nagahiro, Conaway, Ronald C., Conaway, Joan W., Klausner, Richard D., Pause, Arnim
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	National Academy of Sciences 1999
विषय:	Biological Sciences
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12436
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