von Hippel–Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

The transition from transcription initiation to elongation involves phosphorylation of the large subunit (Rpb1) of RNA polymerase II on the repetitive carboxyl-terminal domain. The elongating hyperphosphorylated Rpb1 is subject to ubiquitination, particularly in response to UV radiation and DNA-dama...

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Detalhes bibliográficos
Main Authors: Kuznetsova, Anna V., Meller, Jaroslaw, Schnell, Phillip O., Nash, James A., Ignacak, Monika L., Sanchez, Yolanda, Conaway, Joan W., Conaway, Ronald C., Czyzyk-Krzeska, Maria F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151405/
https://ncbi.nlm.nih.gov/pubmed/12604794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0436037100
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