von Hippel–Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

The transition from transcription initiation to elongation involves phosphorylation of the large subunit (Rpb1) of RNA polymerase II on the repetitive carboxyl-terminal domain. The elongating hyperphosphorylated Rpb1 is subject to ubiquitination, particularly in response to UV radiation and DNA-dama...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kuznetsova, Anna V., Meller, Jaroslaw, Schnell, Phillip O., Nash, James A., Ignacak, Monika L., Sanchez, Yolanda, Conaway, Joan W., Conaway, Ronald C., Czyzyk-Krzeska, Maria F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2003
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12604794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0436037100
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