Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

Mutations of von Hippel–Lindau disease (VHL) tumor-suppressor gene product (pVHL) are found in patients with dominant inherited VHL syndrome and in the vast majority of sporadic clear cell renal carcinomas. The function of the pVHL protein has not been clarified. pVHL has been shown to form a comple...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Iwai, Kazuhiro, Yamanaka, Koji, Kamura, Takumi, Minato, Nagahiro, Conaway, Ronald C., Conaway, Joan W., Klausner, Richard D., Pause, Arnim
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1999
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10535940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.22.12436
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!