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Genetically Targeted Adenovirus Vector Directed to CD40-Expressing Cells

The success of gene therapy depends on the specificity of transgene delivery by therapeutic vectors. The present study describes the use of an adenovirus (Ad) fiber replacement strategy for genetic targeting of the virus to human CD40, which is expressed by a variety of diseased tissues. The tropism...

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Salvato in:
Pubblicato in:J Virol
Autori principali: Belousova, Natalya, Korokhov, Nikolay, Krendelshchikova, Valentina, Simonenko, Vera, Mikheeva, Galina, Triozzi, Pierre L., Aldrich, Wayne A., Banerjee, Papia T., Gillies, Stephen D., Curiel, David T., Krasnykh, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC229360/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14557622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.21.11367-11377.2003
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