Genetically Targeted Adenovirus Vector Directed to CD40-Expressing Cells

The success of gene therapy depends on the specificity of transgene delivery by therapeutic vectors. The present study describes the use of an adenovirus (Ad) fiber replacement strategy for genetic targeting of the virus to human CD40, which is expressed by a variety of diseased tissues. The tropism...

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Bibliographische Detailangaben
Hauptverfasser: Belousova, Natalya, Korokhov, Nikolay, Krendelshchikova, Valentina, Simonenko, Vera, Mikheeva, Galina, Triozzi, Pierre L., Aldrich, Wayne A., Banerjee, Papia T., Gillies, Stephen D., Curiel, David T., Krasnykh, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Gene Therapy
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC229360/
https://ncbi.nlm.nih.gov/pubmed/14557622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.21.11367-11377.2003
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