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A Glycine-Arginine Domain in Control of the Human MRE11 DNA Repair Protein

Human MRE11 is a key enzyme in DNA double-strand break repair and genome stability. Human MRE11 bears a glycine-arginine-rich (GAR) motif that is conserved among multicellular eukaryotic species. We investigated how this motif influences MRE11 function. Human MRE11 alone or a complex of MRE11, RAD50...

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Hlavní autoři: Déry, Ugo, Coulombe, Yan, Rodrigue, Amélie, Stasiak, Andrzej, Richard, Stéphane, Masson, Jean-Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293076/
https://ncbi.nlm.nih.gov/pubmed/18285453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02025-07
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