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Arginine methylation of hnRNPUL1 regulates interaction with NBS1 and recruitment to sites of DNA damage
Arginine methylation is a post-translational modification required for the maintenance of genomic integrity. Cells deficient in protein arginine methyltransferase 1 (PRMT1) have DNA damage signaling defects, defective checkpoint activation and extensive genomic instability. Herein we identify the DN...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4447065/ https://ncbi.nlm.nih.gov/pubmed/26020839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10475 |
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