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Antiviral Therapy during Primary Simian Immunodeficiency Virus Infection Fails To Prevent Acute Loss of CD4(+) T Cells in Gut Mucosa but Enhances Their Rapid Restoration through Central Memory T Cells
Gut-associated lymphoid tissue (GALT) is an early target of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) and a site for severe CD4(+) T-cell depletion. Although antiretroviral therapy (ART) is effective in suppressing HIV replication and restoring CD4(+) T cells in peri...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292978/ https://ncbi.nlm.nih.gov/pubmed/18272585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02164-07 |
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