Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

Salmonella typhimurium causes a localized enteric infection in immunocompetent individuals, whereas HIV-infected individuals develop a life-threatening bacteremia. Here we show that simian immunodeficiency virus (SIV) infection results in depletion of T helper type 17 (T(H)17) cells in the ileal muc...

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Detalhes bibliográficos
Main Authors: Raffatellu, Manuela, Santos, Renato L, Verhoeven, David E, George, Michael D, Wilson, R Paul, Winter, Sebastian E, Godinez, Ivan, Sankaran, Sumathi, Paixao, Tatiane A, Gordon, Melita A, Kolls, Jay K, Dandekar, Satya, Bäumler, Andreas J
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901863/
https://ncbi.nlm.nih.gov/pubmed/18376406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1743
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