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Conversion of agonist site to metal-ion chelator site in the β(2)-adrenergic receptor

Previously metal-ion sites have been used as structural and functional probes in seven transmembrane receptors (7TM), but as yet all the engineered sites have been inactivating. Based on presumed agonist interaction points in transmembrane III (TM-III) and -VII of the β(2)-adrenergic receptor, in th...

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Bibliografske podrobnosti
Main Authors: Elling, Christian E., Thirstrup, Kenneth, Holst, Birgitte, Schwartz, Thue W.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22915/
https://ncbi.nlm.nih.gov/pubmed/10535920
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