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STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7
LKB1, a serine/threonine kinase, regulates cell polarity, metabolism, and cell growth. The activity and cellular distribution of LKB1 are determined by cofactors, STRADα and MO25. STRADα induces relocalization of LKB1 from the nucleus to the cytoplasm and stimulates its catalytic activity. MO25 stab...
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| Glavni autori: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Cell Biology
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291406/ https://ncbi.nlm.nih.gov/pubmed/18256292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0454 |
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