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Nuclear Import of the Thyroid Hormone Receptor α1 is Mediated by Importin 7, Importin β1, and Adaptor Importin α1

The thyroid hormone receptor α1 (TRα1) is a nuclear receptor for thyroid hormone that shuttles rapidly between the nucleus and cytoplasm. Our prior studies showed that nuclear import of TRα1 is directed by two nuclear localization signals, one in the N-terminal A/B domain and the other in the hinge...

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Publicat a:Mol Cell Endocrinol
Autors principals: Roggero, Vincent R., Zhang, Jibo, Parente, Laura E., Doshi, Yazdi, Dziedzic, Rose C., McGregor, Emma L., Varjabedian, Arev D., Schad, Sara E., Bondzi, Cornelius, Allison, Lizabeth A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684427/
https://ncbi.nlm.nih.gov/pubmed/26525414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.10.016
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