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SAT-559 Intranuclear Dynamics of RTHα Mutant Thyroid Hormone Receptors

Abstract: Resistance to Thyroid Hormone α (RTHα), a reduced sensitivity to thyroid hormone (T3) in peripheral tissues, is caused by mutations in thyroid hormone receptor α (TRα), a nuclear receptor that regulates gene expression when bound to T3. These mutations often result in receptors incapable o...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Evans, Rochelle, Roggero, Vincent, Allison, Lizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552555/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-559
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