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Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters
The organization of Ras proteins into nanoclusters on the inner plasma membrane is essential for Ras signal transduction, but the mechanisms that drive nanoclustering are unknown. Here we show that epidermal growth factor receptor activation stimulates the formation of H-Ras.GTP-Galectin-1 (Gal-1) c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291398/ https://ncbi.nlm.nih.gov/pubmed/18234837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1053 |
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