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In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease
AIMS: The aims of this study were to visualize in vivo binding of donepezil to acetylcholinesterase (AChE) in the brain and to establish a method for measuring the amount of binding of orally administered donepezil. METHODS: [5-(11)C-methoxy]-donepezil ([(11)C]-donepezil) was radiolabelled as a posi...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291371/ https://ncbi.nlm.nih.gov/pubmed/18070217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03063.x |
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