Brain histamine H(1) receptor occupancy after oral administration of desloratadine and loratadine

Some histamine H(1) receptor (H(1)R) antagonists induce adverse sedative reactions caused by blockade of histamine transmission in the brain. Desloratadine is a second‐generation antihistamine for treatment of allergic disorders. Its binding to brain H(1)Rs, which is the basis of sedative property o...

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Dades bibliogràfiques
Publicat a:Pharmacol Res Perspect
Autors principals: Nakamura, Tadaho, Hiraoka, Kotaro, Harada, Ryuichi, Matsuzawa, Takuro, Ishikawa, Yoichi, Funaki, Yoshihito, Yoshikawa, Takeo, Tashiro, Manabu, Yanai, Kazuhiko, Okamura, Nobuyuki
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624455/
https://ncbi.nlm.nih.gov/pubmed/31338198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.499
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