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No significant effect of SLCO1B1 polymorphism on the pharmacokinetics of rosiglitazone and pioglitazone

AIMS: To examine possible effects of polymorphism in the SLCO1B1 gene, encoding the hepatic uptake transporter organic anion transporting polypeptide (OATP) 1B1, on the pharmacokinetics of rosiglitazone and pioglitazone in a prospective genotype panel study. METHODS: Sixteen healthy volunteers with...

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Detalhes bibliográficos
Main Authors: Kalliokoski, Annikka, Neuvonen, Mikko, Neuvonen, Pertti J, Niemi, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291278/
https://ncbi.nlm.nih.gov/pubmed/17635496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02986.x
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