Effect of SLCO1B1 genetic polymorphism on the pharmacokinetics of nateglinide

AIMS: Nateglinide is a meglitinide analogue with antidiabetic action. A recent study showed that SLCO1B1 (which codes the OATP1B1 gene, also known as OATP-C, OATP2) is a major determinant which markedly affects the pharmacokinetics of repaglinide. Our objective was to assess the association between...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, He, Yi-Jing, Han, Chun-Ting, Liu, Zhao-Qian, Li, Qing, Fan, Lan, Tan, Zhi-Rong, Zhang, Wei-Xia, Yu, Bang-Ning, Wang, Dan, Hu, Dong-Li, Zhou, Hong-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885174/
https://ncbi.nlm.nih.gov/pubmed/16796707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02686.x
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