SLCO1B1 521T→C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients

What is already known about this subject: Both oral clearance as well as delivery of pravastatin to its molecular targets in hepatoctyes are greatly influenced by the organic anion transporting polypeptide 1B1 (OATP1B1), encoded by SLCO1B1. The role of genetic factors that determine the marked inter...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, Chen, Bi-Lian, Ozdemir, Vural, He, Yi-Jing, Zhou, Gan, Peng, Dao-Di, Deng, Sheng, Xie, Qi-Ying, Xie, Wei, Xu, Lin-Yong, Wang, Lian-Ci, Fan, Lan, Wang, An, Zhou, Hong-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000640/
https://ncbi.nlm.nih.gov/pubmed/17439540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02892.x
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