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Effect of rifampicin on the pharmacokinetics of pioglitazone

AIMS: The effect of enzyme induction on the pharmacokinetics of pioglitazone, a thiazolidinedione antidiabetic drug that is metabolized primarily by CYP2C8, is not known. Rifampicin is a potent inducer of several CYP enzymes and our objective was to study its effects on the pharmacokinetics of piogl...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jaakkola, Tiina, Backman, Janne T, Neuvonen, Mikko, Laitila, Jouko, Neuvonen, Pertti J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884976/
https://ncbi.nlm.nih.gov/pubmed/16390353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02515.x
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