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Effect of rifampicin on the pharmacokinetics of pioglitazone

AIMS: The effect of enzyme induction on the pharmacokinetics of pioglitazone, a thiazolidinedione antidiabetic drug that is metabolized primarily by CYP2C8, is not known. Rifampicin is a potent inducer of several CYP enzymes and our objective was to study its effects on the pharmacokinetics of piogl...

詳細記述

保存先:
書誌詳細
主要な著者: Jaakkola, Tiina, Backman, Janne T, Neuvonen, Mikko, Laitila, Jouko, Neuvonen, Pertti J
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884976/
https://ncbi.nlm.nih.gov/pubmed/16390353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2005.02515.x
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