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Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects

AIMS: Previous work has shown that rifampicin, a potent inducer of several cytochrome P450 (CYP) enzymes and transporters, decreased the plasma concentrations of simvastatin acid by more than 90%. This study was conducted to investigate the effect of rifampicin on the pharmacokinetics of pravastatin...

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Detalhes bibliográficos
Main Authors: Kyrklund, Carl, Backman, Janne T, Neuvonen, Mikko, Neuvonen, Pertti J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884432/
https://ncbi.nlm.nih.gov/pubmed/14748817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01972.x
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